Balling drum mixer is a kind of mixing equipment that mixes materials through drum rotation，and its parameters have different effects on the granulation effect. In order to optimize the parameters of the drum mixer and improve the granulation process，EDEM software is used as the platform to establish a simulation analysis model，simulate and analyze the rotation speed，granulation time and filling rate of the drum mixer in the process of sintering mixing，and then carry out sintering tests，manually add water to the mixture to mix evenly，so that the moisture，particle size and components in the mixture are evenly distributed，and the wetting and preheating mixture is supplemented in the drum mixer，and the optimal parameters during the operation of the drum mixer are determined through the granulation test. The results show that increasing the filling rate and increasing the speed of the mixer have a certain impact on the particle mixing. When the filling rate is less than 11% ，the globules are gradually increased，and the average particle size of the globules is increased. When the filling rate is 11% ，the mixing effect is the best，and the filling rate continues to increase，and the mixing effect is gradually decreased. When the rotation speed is less than 24 r/min，the globules are gradually increased，and the average particle size of the globules is increased，and the effect is best when the rotation speed is 24 r/min. With the extension of granulation time，the particle mixing degree first increases and then tends to be stable，and the particle mixing gradually becomes uniform when the granulation time is less than 5 min，and the mixing effect is best when the granulation time reaches 5 min. The simulation and analysis obtained by EDEM software are basically consistent with the actual test results.