Low-temperature waste heat power generation is one of the key paths to solve the current high energy consumption and low waste heat utilization rate in our country’s industrial field. The organic Rankine cycle （ORC） has attracted much attention for significantly improving expander efficiency and improving the power generation performance of steam turbines under low temperature conditions. Based on system constitution and refrigerant selection， the working principle，technical characteristics and the influence of working fluid physicochemical properties on performance are expounded，and then the system configuration， key equipment， working fluid scheme and operating parameters of the demonstration projects that have been put into operation in steel，chemical，petrochemical and other industries are sorted out，and their energy conservation， environmental protection and economic benefits are evaluated by using net power generation，thermal efficiency and payback period as indicators. The analysis results show that ORC can achieve kW to MW power generation according to the scale of waste heat and working fluid characteristics，and the efficiency can be improved after the introduction of heat recovery，duplex or tandem stage，and the payback period can be controlled within 2 years. R245fa，R134a and other dry fluids are the preferred working fluids，and non-azeotropic working fluids need to solve the problem of composition drift. The low-temperature waste heat power generation demonstration project in the steel，chemical and petrochemical industries has confirmed that ORC has the conditions for large-scale promotion. Through the case analysis，it provides reference for the large-scale promotion of ORC technology in low-temperature waste heat power generation，and provides reference for the design and application of waste heat utilization in more industrial scenarios.