Based on the experiment and CFD-DEM model analysis, the erosion of 90° elbow pipe wall in sintering dust removal system is studied, and the effects of dust concentration, pipe velocity, particle diameter, pipe bend-diameter ratio and pipe diameter on the erosion rate of elbow are analyzed. The simulation results are verified with the experimental values, and the simulation results are in good agreement with the experimental data, which shows that the simulation results are basically reliable. The maximum erosion rate of elbow increases linearly with the increase of dust concentration, and when the dust concentration is different, the maximum erosion rate is basically the same, mainly concentrated in 50° ~ 70°; The maximum erosion rate of elbow increases exponentially with the increase of pipeline velocity. When the pipeline velocity is greater than 15 m/s, the erosion rate increases obviously. With the increase of dust particle size, the maximum erosion rate of elbow increases, but when the particle diameter is greater than 150 μm, the increase rate of maximum erosion rate decreases with the increase of particle size. The erosion rate decreases with the increase of elbow-diameter ratio; The wall erosion rate decreases with the increase of pipe diameter. The results can provide a theoretical reference for the research and engineering design of elbow erosion and wear resistance.