Rotary kiln process is widely used in the resource disposal of zinc-containing solid waste. In order to optimize the technique, in this paper, based on comparing and studying the composition and phase of incoming charge, tailings and recycled zinc powder of two enterprises, the reaction process of rotary kiln is analyzed. The results show that the removal rates of Pb and Zn produced from two kinds of inc-containing wastes are 83.33%, 67.69%, 96.97% and 84.38% respectively, the grades of purity of regenerated zinc powder are 14.58% and 41.49% respectively, the removal rates of Cl are 96.64% and 97.97% respectively. In numerical simulation, when the ventilation rate is 10 m/s and the temperature of insulated wall is 1200 ℃, the step separation of Pb, Zn and Fe-containing kiln slag can be realized. This method is conducive to improve the purity of regenerated products and enhance the value of zinc-containing solid waste.