The CO in sintering flue gas badly requires treatment before emission. The catalytic oxidation is a highly feasible method to remove CO in the sintering flue gas. However, most of the catalysts are at risk of being poisoned by SO₂ in the low-temperature sintering flue gas. Among the various catalysts for CO oxidation, Pt catalyst has high activity and excellent anti-SO₂ performance, and has great application prospects in the field of CO purification of sintering flue gas. In this article, the poisoning mechanism of SO₂ to Pt catalysts, the influence factors and the regeneration methods are summarized. The content shows that, the sulfate, sulfite, sulfuric acid, and Pt-SO_x are formed by SO₂ on the catalyst to covers its active sites and to change its structures. The factors influencing the SO₂-resistance property of catalysts includes the carrier acidity and bore size, Pt particle size and valence state, and reaction gas. The regeneration method is mainly heating in a reducing gas stream to desorb and decompose the poisonous products. The impact factors on regeneration effect include the carrier component, the Pt particle size, and the regeneration temperature. In addition, according to domestic and foreign literature, by focusing on the influencing factors of poisoning and regeneration, such as increasing carrier acidity and pore size, tuning Pt particle size, increasing zero valent Pt, and raising regeneration temperature, the anti-SO₂ performance and the regeneration effect could be enhanced. At last, based on the current research status of SO₂-resistant Pt catalysts and their regeneration methods, suggestions and perspectives for the rational design of the CO oxidation catalysts for the sintering flue gas are proposed.