According to the limitation of the raw material resources of Xichang steel and vanadium, the material structure of sintering and blast furnace is frequently adjusted, which is unfavorable to the production. In this paper, the development process of producing acid vanadium titanium sinter with vanadium-bearing titanomagnetite concentrate instead of raw ore is introduced. The results showed that optimal quality and yield of acidic sinter could be obtained when the ratio of fuel was 5%, the basicity of sinter was 0.6 and the content of TiO₂ was 5.5%. After acidic vanadium-bearing titanomagnetite sinter was used to replace raw ore, the amount of harmful element brought in by material were reduced and the reduction of TiO₂ was prohibited. During the industrial test, improving the ratio of pellet, developing central gas flow, improving the rate of oxygen enrichment, top pressure and the stability of furnace temperature, the operation of blast furnace was successful, the utilization coefficient of blast furnace increased by 0.082 t/(m³·d), iron loss decreased by 0.51% and fuel rate decreased by 5.47 kg/t.